Adam Mastroianni identifies the real reason for the lack of scientific progress:

I certainly believe that Nature makes some mysteries easier to untangle than others—it’s easier to study Earth than it is to study Pluto—and some of those mysteries might be unsolvable entirely. But the main limit to scientific inquiry isn’t reality. It’s us.

Indeed.

@JohnBrady That is a terrific observation. In biotech, the interpretive dance consists of setting up your animal models just-so in order to get the results you want.